The combination of sulfadiazine and trimethoprim acts synergistically and usually bactericidal against many Gram-positive and Gram-negative bacteria. Both compounds aect bacterial purine synthesis in a dierent way, as a result of which a double blockade...

Enrofloxacin belongs to the group of quinolones and acts bactericidal against mainly Gram-negative bacteria including anaerobic pathogens. The most important micro-organisms are:like Campylobacter, E. coli Haemophilus, Pasteurella ., Staphylococcus spp., Streptococcus spp., Klebsiella spp., Pseudomonas,...

Norfloxacin is a fluorinated 4-quinolone antimicrobial agent which is bactericidal against most Gram-positive bacteria and Gram-negative bacteria like Campylobacter, E. coli, Haemophilus, Pasteurella Salmonella, and Mycoplasma spp, including Pseudomonas aeruginosa and Mycoplasma.

Colistin is an antibiotic from the group of polymyxins with bactericidal action against Gramnegative bacteria like E. coli, Haemophilus and Salmonella spp. Polymyxins interact strongly with phospholipids and penetrate into and disrupt the structure of...